By Richard G. Mackay, Jennifer M. Tait
Chitosan is deacetylated by-product of chitin, a usual polysaccharide extracted from crustaceans, bugs and sure fungi. as a result of its detailed houses comparable to biodegradability, biocompatability, organic job and means of forming polyelectrolyte advanced with anionic polyelectrolytes, chitosan has been commonly utilized within the nutrients and cosmetics undefined, in addition to the biomedical box in terms of tissue engineering, and the pharmaceutical with regards to drug supply. This guide gathers present learn from world wide within the examine of chitosan and its functions.
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Extra resources for Handbook of chitosan research and applications
Process and system for separation of organic charged compounds. Patent Pending PCT/CA2005/000337. , Porter, A. (2005b). Electromigration of tobacco polyphenols. Separation and Purification Technology, 41, 101-107. , Porter, A. (2005c). Enhanced tobacco polyphenol electromigration and impact on membrane integrity. Journal of Membrane Science, 254, 111-118. , Firdaous, L. (2009). Membrane processes and devices for separation of bioactive peptides. Recent Patents on Biotechnology, 3, 61-72. , Lin Teng Shee, F.
The synthesized TMC with different DQs were studied for their physicochemical properties namely solubility. Their cytotoxicity (MTT assay and LDH release) and the ability to open tight junctions (transepithelial electrical resistance, TEER), were measured and compared with TMC synthesized via the traditional method. Results showed that the DQ of the TMC could be tailored by varying the reaction time. O-Methyl free TMCs with a DQ>33% were readily soluble in aqueous solutions at pH 7. The O-methyl free TMCs demonstrated a larger decrease in TEER of Caco-2 cells than O-methylated TMCs pointing at their higher penetration enhancing effect.
Bioscience, Biotechnology and Biochemistry, 5, 965-971. Y. (2001). In vitro antimicrobial activity of chitooligosaccharide mixture against Actinobacillus actinomycetemcomitans and Streptococcus mutans. International Journal of Antimicrobial Agents, 18, 553-557. C. (2004). Relationship between antibacterial activity of chitosan and surface characteristics of cell wall. Acta Pharmacologica Sinica, 25, 932-936. , Pedersen, C. (1989). Chitin and chitosan oligosaccharides. ; Sandford, P. 415-429. , Cartier, N.