By Gisela Dallenbach-Hellweg M.D., F.I.A.C., Hemming Poulsen M.D. (auth.)
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Additional info for Atlas of Endometrial Histopathology
A) normal secretory phase, if it corresponds to the day of the menstrual cycle; (b) deficient secretory phase with coordinated true delay, if the day of the menstrual cycle is 3-lO days further advanced than the histologic differentiation; (c) normal secretory phase in amenorrhea due to silent menstruation (Philippe et al. 1966). Distinction is possible only by precise statement of the day of the menstrual cycle and/or recording of the basal body temperature curve. Menstruation The first day of menstruation (Figs.
The cytoplasm is scanty. Spiral arterioles are undeveloped. In early stages, a few glands may still remain in deficient proliferation or be resting and become atrophic gradually. The extent of atrophy with total or subtotal loss of glands and more or less complete absence of enzymes and glycoproteins is a measure of the severity and duration of the underlying change (Goldberg and Jones 1956; McKay et al. 1956; Lewin 1961; Gross 1964). Clinical Possibilities and Differential Diagnosis. (a) Nonfunctioning ovaries before puberty and in the postmenopause or due to a central or ovarian defect; (b) refractive endometrium; (c) iatrogenic suppression by gestagens (as with long-term use of oral contraceptives) or anti estrogens.
Serous papillary syncytial metaplasia of endometrial glands with hobnail cell change. H & E, X350 Fig. 62. Clear cell metaplasia with occasional hobnail nuclei. H & E, X350 Stromal Metaplasia 47 stituents of the endometrium, only larger accumulations of these cells should be called metaplasia. Rare Forms of Metaplasia of Endometrial Glandular Epithelium Rare forms include clear cell metaplasia (Fig. 62), possibly derived from maldeveloped mucinous cells, and eosinophilic (oncocytic) metaplasia (Fig.